The stenosis and embolization of internal fistula vessels directly affect the clinical treatment effect of maintenance hemodialysis patients,and the study of the mechanism of internal fistula stenosis has become a research hotspot in recent years.Previous studies mainly focused on the hemodynamics and pathophysiology of blood vessel wall,and there were few studies on molecular biology and its related signaling pathways.This paper reviews the hemodynamics of the vascular pathway of internal arteriovenous fistula(AVF),the pathophysiological mechanism,molecular biology,and changes in various signaling pathways of AVF dysfunction at home and abroad,in order to provide references for the study of AVF dysfunction.
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