Anti γ-aminobutyric acid B receptor encephalitis is a type of autoimmune encephalitis characterized by the production of self specific antibodies in cerebrospinal fluid and/or serum,with seizures,memory loss,and consciousness disorders as the main clinical manifestations.This type of encephalitis caused by autoantibodies has the same pathological characteristics as other peripheral encephalitis.There are many different etiologies and pathophysiological processes that lead to the occurrence of limbic encephalitis,and it is necessary to understand their heterogeneity in order to find effective treatment methods.This article will systematically review the epidemiology,pathogenesis,clinical characteristics,diagnosis,treatment,and prognosis of anti γ-aminobutyric acid B receptor encephalitis,aiming to enhance clinical doctors'understanding of this disease and provide reference for clinical decision-making.