中国医师杂志2024,Vol.26Issue(8) :1273-1276.DOI:10.3760/cma.j.cn431274-20230927-00329

抗凝相关脑出血重启抗凝治疗的研究进展

Research progress on restarting anticoagulant therapy for anticoagulation related cerebral hemorrhage

泮旭峰 吴蓉 柴海飞 汪杰 胡小铭
中国医师杂志2024,Vol.26Issue(8) :1273-1276.DOI:10.3760/cma.j.cn431274-20230927-00329

抗凝相关脑出血重启抗凝治疗的研究进展

Research progress on restarting anticoagulant therapy for anticoagulation related cerebral hemorrhage

泮旭峰 1吴蓉 2柴海飞 1汪杰 1胡小铭1
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作者信息

  • 1. 浙江省台州医院神经外科,台州 317000
  • 2. 临海市第一人民医院内科,台州 317000
  • 折叠

摘要

随着人口老龄化,房颤、静脉血栓等疾病负担逐渐加重,抗凝治疗在预防上述患者缺血性卒中、肺栓塞等方面具有肯定意义.但老人跌倒事件、脑血管意外、车祸等导致颅内出血而引起的疾病状态时,抗凝治疗会起到相反的作用.在脑出血后是否重启抗凝及何时重启抗凝仍难以决断.虽然大多研究显示重启抗凝治疗可降低卒中风险且出血风险无显著升高,但多基于观察性研究,因此需要更多的高质量研究以指导临床决策.本文综述重启抗凝方面的研究进展,以期对临床应用有一定的帮助.

Abstract

With the aging population,the burden of diseases such as atrial fibrillation and venous thrombosis is gradually increasing.Anticoagulant therapy has a positive significance in preventing ischemic stroke,pulmonary embolism,and other related conditions in these patients.However,anticoagulant therapy can have the opposite effect on diseases caused by intracranial hemorrhage,such as falls in the elderly,cerebrovascular accidents,and car accidents.It is still difficult to determine whether and when to restart anticoagulation after cerebral hemorrhage.Although most studies have shown that restarting anticoagulant therapy can reduce stroke risk without significantly increasing bleeding risk,they are mostly based on observational studies,so more high-quality research is needed to guide clinical decision-making.This article reviews the research progress on restart anticoagulation,aiming to provide some assistance for clinical applications.

关键词

抗凝药/脑出血/重启抗凝

Key words

Anticoagulants/Cerebral hemorrhage/Restart

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基金项目

台州市科技计划项目(20ywb15)

出版年

2024
中国医师杂志
中华医学会 湖南省医学会

中国医师杂志

CSTPCD
影响因子:0.876
ISSN:1008-1372
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