Clinical efficacy of ultrasound-guided spinal nerve block and paraverteral nerve block in treating postherpetic neuralgia
Objective To compare the clinical efficacy of ultrasound-guided spinal nerve block(SNB)and paraverteral nerve block(PVB)in treating postherpetic neuralgia.Methods A total of 52 patients with postherpetic neuralgia who visited the Pain Clinic of the Xiangya Hospital,Central South University from February 2020 to December 2022 were selected and randomly divided into an ultrasound-guided SNB group and a PVB group using a random number table method,with 26 patients in each group.Patients in the SNB group received ultrasound-guided spinal nerve block therapy;The PVB group received ultrasound-guided paraverteral nerve block treatment.Visual Analog Scale(VAS)scores,36-Item Short Form Survey(SF-36)scores,and total effective rate were observed in two groups of patients before treatment,2 weeks after treatment,1 month after treatment,3 months after treatment,and 6 months after treatment.Complications during treatment were also observed.Results The total effective rates of SNB group patients at 1,3,and 6 months after treatment were significantly higher than those of PVB group(all P＜0.05).After treatment,the VAS scores of both groups of patients at each time point were significantly reduced compared to before treatment(all P＜0.05);The VAS scores of patients in the SNB group were lower than those in the PVB group at 1,3,and 6 months after treatment,but the difference was not statistically significant(all P＞0.05).There was no statistically significant difference in Physical Component Summary(PCS)and Mental Component Summary(MCS)scores between SNB and PVB groups before nerve block treatment(all P＞0.05).The MCS and PCS scores of the two groups of patients were significantly higher than before treatment at 2 weeks,1 month,3 months,and 6 months after treatment(all P＜0.05).The MCS scores of the SNB group were significantly higher than those of the PVB group at 2 weeks,1 month,3 months,and 6 months after treatment(all P＜0.05),but there was no statistically significant difference in PCS scores between the two groups(all P＞0.05).Both groups of patients did not experience any serious complications related to the treatment in this study during the follow-up period.Conclusions Both ultrasound-guided spinal nerve block and paraverteral nerve block can safely and effectively treat postherpetic neuralgia.The clinical effect of ultrasound-guided spinal nerve block in treating postherpetic neuralgia is better than that of paraverteral nerve block.
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