The effect of Shuanghuakun pregnancy formula combined with thunder fire moxibustion on clinical symptoms and ovarian function in patients with endometriosis
Objective To analyze the effects of Shuanghuakun pregnancy formula combined with thunder fire moxibustion on clinical symptoms and ovarian function in patients with endometriosis(EMT).Methods A retrospective study was conducted on 90 patients with EMT who visited Hebei Academy of Traditional Chinese Medicine and Shijiazhuang Hospital of Traditional Chinese Medicine from July 2021 to July 2023.They were divided into two groups,with 45 patients in each group,based on different treatment methods.The control group was treated with gestrinone capsules,while the observation group was treated with Shuanghuakun pregnancy formula combined with thunder fire moxibustion.The clinical efficacy,clinical symptom scores,ovarian function,and serum cytokines before and after treatment were compared between the two groups.Results The total effective rate of the observation group[95.56％(43/45)]was higher than that of the control group[68.89％(31/45)](P＜0.05).After treatment,the observation group had lower scores of non menstrual anal pain,sexual pain,non menstrual lower abdominal pain,and menstrual abdominal pain than the control group(all P＜0.05).After treatment,the serum follicle stimulating hormone(FSH)level in the observation group was lower than that in the control group(P＜0.05),and the number of antral follicles and ovarian volume were greater than those in the control group(all P＜0.05).After treatment,the levels of serum carbohydrate antigen 125(CA125),tumor necrosis factor-α(TNF-α),and vascular endothelial growth factor(VEGF)in the observation group were lower than those in the control group(all P＜0.05).Conclusions The combination of Shuanghuakun pregnancy formula and thunder fire moxibustion can effectively alleviate symptoms such as abdominal pain in EMT patients,improve ovarian function,reduce serum FSH,CA125,TNF-α,and VEGF levels,and enhance treatment efficacy.
EndometriosisShuanghuakun pregnant formulaLightning moxibustionOvarian function
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