首页|铁死亡在皮肤疾病研究中的新视角与展望

铁死亡在皮肤疾病研究中的新视角与展望

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铁死亡被认为是一种新型的、可调控的细胞死亡形式,其主要特征为铁代谢异常和脂质过氧化物的累积。尽管铁死亡在肿瘤、退行性疾病的研究中有了突破性进展,但在皮肤疾病中的研究相对较少。本文从铁死亡概念的发展出发,阐述了铁死亡的基本特征及调控机制。针对皮肤疾病领域,笔者强调了铁死亡在该领域的重要性,并详细探讨了铁死亡在各类皮肤疾病中的研究以及应用,旨在为各类皮肤疾病的治疗、临床实践提供有效指导,为未来皮肤疾病的研究方向提供新的思路。
New perspectives and prospects of ferroptosis in the research of skin diseases
Ferroptosis is regarded as a novel and regulatable form of cell death,with its main characteristics being abnormal iron metabolism and the accumulation of lipid peroxides.Although there have been breakthroughs in the research of ferroptosis in tumors and degenerative diseases,its research in skin diseases is relatively scarce.Starting from the development of the concept of ferroptosis,this article expounds the basic characteristics and regulatory mechanisms of ferroptosis.In the field of skin diseases,we emphasize the importance of ferroptosis and discuss in detail the research and application of ferroptosis in various skin diseases,aiming to provide effective guidance for the treatment and clinical practice of various skin diseases,and offer new ideas for the future research direction of skin diseases.

FerroptosisSkin diseases

唐宁宁、黄晓元、刘洋、李福英、徐丹、衷驰、周建大

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湘雅常德医院整形美容科,常德 415000

中南大学湘雅三医院整形外科,长沙 410013

铁死亡 皮肤疾病

2024

中国医师杂志
中华医学会 湖南省医学会

中国医师杂志

CSTPCD
影响因子:0.876
ISSN:1008-1372
年,卷(期):2024.26(9)