首页|超声剪切波弹性成像及超声造影术在经直肠前列腺穿刺活检中的应用价值

超声剪切波弹性成像及超声造影术在经直肠前列腺穿刺活检中的应用价值

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目的 研究超声剪切波弹性成像(SWE)技术与超声造影(CEUS)术在经直肠前列腺穿刺活检中的应用价值。方法 回顾性分析2017年5月至2019年5月在内蒙古医科大学附属医院行经直肠前列腺穿刺活检的100例患者临床资料,根据穿刺方法分为SWE组(54例)和CEUS组(46例)。SWE组采用SWE辅助经直肠前列腺穿刺活检,CEUS组采用CEUS进行前列腺穿刺活检。记录SWE、CEUS对前列腺癌的检出情况,并以穿刺活检病理检查结果作为金标准,比较分析两组检查结果的灵敏度、特异度及准确度。结果 SWE检出前列腺癌35例,前列腺增生19例,病理证实SWE组38例为前列腺癌,16例为前列腺增生,共451针,平均为(8。35±1。67)针/例。CEUS检出前列腺癌28例,前列腺增生18例,CEUS组病理证实36例为前列腺癌,10例前列腺增生,共462针,平均为(10。04±1。33)针/例。两种检查方法穿刺次数差异有统计学意义(P<0。05)。两组患者年龄、体重指数及病理结果差异均无统计学意义(均P>0。05)。两组阳性检出率、灵敏度和特异度差异均无统计学意义(均P>0。05)。SWE组准确度显著高于CEUS组,差异具有统计学意义(P<0。05)o SWE组前列腺癌患者的Emean与Emax显著高于前列腺增生患者(P<0。05)。受试者工作特征(ROC)曲线分析显示,Emean 诊断前列腺癌的 AUC 为0。752(95%CI=0。611~0。894,P=0。007),最佳截断值为47。005 kPa。结论 SWE与CEUS辅助经直肠前列腺穿刺活检均可获得较高的前列腺癌阳性检出率,SWE辅助经直肠前列腺穿刺可为预测前列腺癌提供定量依据,提高诊断准确性。
Application value of ultrasonic shear wave elastography and ultrasonography in transrectal prostate biopsy
Objective To study the value of ultrasonic shear wave elastography(SWE)and contrast-enhanced ultrasound(CEUS)in transrectal prostate biopsy.Methods Clinical data of 100 patients who underwent transrectal prostate biopsy in The Affiliated Hospital of Inner Mongolia Medical University from May 2017 to May 2019 were retrospectively analyzed,and they were divided into SWE group(54 cases)and CEUS group(46 cases)according to puncture methods.Swe-assisted transrectal prostate biopsy was performed in the SWE group and CEUS group.The detection of prostate cancer by SWE and CEUS was recorded,and the sensitivity,specificity and accuracy of the two groups were compared with the biopsy results as the gold standard.Results SWE detected 35 cases of prostate cancer and 19 cases of prostate hyperplasia,and pathologically confirmed 38 cases of prostate cancer and 16 cases of prostate hyperplasia in SWE group,with a total of 451 needles,with an average of(8.35±1.67)needles/case.There were 28 cases of prostate cancer and 18 cases of prostatic hyperplasia detected by CEUS,36 cases of prostate cancer and 10 cases of prostatic hyperplasia confirmed by pathology in CEUS group,with a total of 462 needles,with an average of(10.04±1.33)needles/case.There was significant difference in puncture times between the two methods(P<0.05).There were no significant differences in age,body mass index and pathological results between 2 groups(all P>0.05).There were no significant differences in positive detection rate,sensitivity and specificity between the two groups(all P>0.05).The accuracy of SWE group was significantly higher than CEUS group,and the difference was statistically significant(P<0.05).The Emean and Emax levels in patients with prostate cancer in SWE group were significantly higher than those in patients with prostate hyperplasia(P<0.05).Receiver operating characteristic(ROC)curve analysis showed that the area under the curve(AUC)for Emean diagnosis of prostate cancer was 0.752(95%CI=0.611-0.894,P=0.007),and the optimal cut-off value was 47.005 kPa.Conclusions Both SWE and CEUS assisted transrectal prostate biopsy can obtain higher positive rates of prostate cancer.SWE assisted transrectal prostate biopsy can provide quantitative basis for predicting prostate cancer and improve diagnostic accuracy.

Prostatic diseasesBiopsy,needleElasticity imaging techniquesContrast-enhanced ultrasound

沙仁高娃、张军

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内蒙古医科大学附属医院超声医学科,呼和浩特 010110

内蒙古医科大学附属医院泌尿外科,呼和浩特 010110

前列腺疾病 活组织检查,针吸 弹性成像技术 超声造影成像

内蒙古自然科学基金

2020MS08047

2024

中国医师杂志
中华医学会 湖南省医学会

中国医师杂志

CSTPCD
影响因子:0.876
ISSN:1008-1372
年,卷(期):2024.26(10)