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乙型肝炎阳性孕产妇服务利用情况分析

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目的 了解乙型肝炎(简称乙肝)阳性孕产妇的乙肝检测、孕产期保健和抗病毒治疗的情况,为实现消除乙肝母婴传播目标提供科学依据。方法 收集国家预防艾滋病、梅毒和乙肝母婴传播(IPMTCT)信息管理系统中湖南省在2021-2023年期间的乙肝阳性孕产妇个案登记卡相关信息。回顾性分析孕产妇乙肝检测情况、乙肝阳性孕产妇人口学特征、分娩方式、抗病毒用药等情况。结果 2021-2023年湖南省孕产妇乙肝检测率为99。99%(1 196 261/1 196 370),孕产妇乙肝阳性检出率逐年下降(x2趋势=37。570,P<0。001)。确诊的75 542例乙肝阳性孕产妇文化程度普遍较低,以中学为主(占63。4%,47 893例);乙肝阳性孕产妇孕早期确诊比例逐年升高(x2趋势=414。202,P<0。001),乙肝阳性孕产妇的分娩方式以自然分娩和择期剖宫产为主,高母婴传播风险乙肝阳性孕产妇用药率由 47。4%(924/1 949)上升至 80。9%(2 238/2 768)(x2趋势=570。003,P<0。001)。结论 需加强乙肝阳性孕产妇的健康教育,优化高母婴传播风险乙肝阳性孕产妇抗病毒治疗的管理流程,进一步提高抗病毒治疗率,从而降低乙肝母婴传播风险。
Analysis of service utilization of hepatitis B positive pregnant women
Objective To understand the status of hepatitis B detection,prenatal care and antiviral treatment for hepatitis B positive pregnant women,and to provide scientific basis for the elimination of mother-to-child transmission of hepatitis B.Methods The information of hepatitis B positive maternal case registration cards in Hunan Province during 2021-2023 was collected from the National Integrated Prevention of human immunodeficiency virus/acquired immune deficiency syndrome(HIV/AIDS),syphilis and hepatitis B mother-to-child transmission(IPMTCT)information management system.The status of hepatitis B detection,demographic characteristics of hepatitis B positive pregnant women,delivery methods,antiviral drugs and so on were analyzed retrospectively.Results The hepatitis B detection rate of pregnant women in Hunan Province from 2021 to 2023 was 99.99%(1 196 261/1 196 370),and the positive rate of hepatitis B decreased year by year(x2trend=37.570,P<0.001).The education level of 75 542 hepatitis B positive pregnant women was generally low,and most of them were middle schools(63.4%,47 893 cases).The proportion of hepatitis B positive pregnant women diagnosed in early pregnancy increased year by year(x2trend=414.202,P<0.001).The delivery mode of hepatitis B positive pregnant women were mainly natural childbirth and elective cesarean section.The rate of hepatitis B positive pregnant women with high risk of mother-to-child transmission increased from 47.4%(924/1 949)to 80.9%(2 238/2 768)(x2trend=570.003,P<0.001).Conclusions It is necessary to strengthen the health education of hepatitis B positive pregnant women,optimize the management process of antiviral treatment for hepatitis B positive pregnant women with high risk of mother-to-child transmission,and further improve the rate of antiviral treatment,so as to reduce the risk of mother-to-child transmission of HBV.

Hepatitis BMaternal healthMother-to-child transmission

高洁、杨敏、吴颖岚、陈霞、梁婷、曾梦君

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湖南省妇幼保健院妇女保健科,长沙 410008

湖南省妇幼保健院营养科,长沙 410008

乙型肝炎 孕产妇健康 母婴传播

2024

中国医师杂志
中华医学会 湖南省医学会

中国医师杂志

CSTPCD
影响因子:0.876
ISSN:1008-1372
年,卷(期):2024.26(12)