Objective To evaluate the accuracy and reliability of high frequency ultrasound in measuring the penetration depth of hypertrophic scar with ultra-pulse CO2 fractional laser.Methods From February 2022 to February 2023,10 cases of hypertrophic scar tissue underwent surgical resection in the Hunan Provincial People's Hospital were collected.After irradiating the hypertrophic scar tissue with different energy ultra-pulse CO2 dot matrix laser,high-frequency ultrasound was used to observe and identify the laser gasification holes and tissue degeneration areas in the scar.The same scar tissue was histopathically sliced and the images of laser vaporized pores and tissue degeneration area were collected after hematoxylin-eosin(HE)staining,and the correlation and consistency of the two results of high-frequency ultrasound and pathological tissue section were compared and analyzed.Results There was a strong positive correlation between the results of laser channel depth measured by pathological section and the results of laser channel depth measured by high-frequency ultrasound and the depth of tissue degeneration area(r=0.976,0.927,all P＜0.001).Among them,the results of pathological section and high-frequency ultrasound measured laser channel depth were highly consistent,and could be used interchangeably in clinical work.Conclusions High-frequency ultrasound can be used to evaluate the change of scar internal condition after ultra-pulsed CO2 dot matrix laser irradiation,and measure the penetration depth of laser on scar tissue.The measurement results have high accuracy and reliability.
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