Objective To review the relationship between severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and cognitive dysfunction and the mechanism of cognitive dysfunction in post-COVID-19 syndrome.Methods CNKI and PubMed databases were searched to collect relevant research reports on cognitive dysfunction after SARS-CoV-2 infection by traditional Chinese medicine(TCM)and western medicine from January 1,2020 to October 30,2023.Results Cognitive dysfunction might occur after SARS-CoV-2 infection,which might be related to the neuroaggressive,neurotropic,and neurovirulent nature of the SARS-CoV-2 virus,or to factors such as post-infection-mediated hyperinflammation,serotonin levels,and viral metastasis.It was also found that some TCM monomers had the effect of improving cognitive dysfunction after SARS-CoV-2 infection.Conclusion Cognitive dysfunction may occur for a short time or for a long time after SARS-CoV-2 infection,and its mechanism needs to be further verified by clinical and basic research.
关键词
新型冠状病毒/新冠后遗症/认知功能障碍/中药/神经
Key words
severe acute respiratory syndrome coronavirus 2/post-COVID-19 syndrome/cognitive dysfunction/traditional Chinese medicine/nerve
维普
万方数据