Monkeypox(Mpox)is a disease caused by infection with the monkeypox virus(MPXV).There is no specific therapeutic drug for monkeypox virus in the world,and antiviral drugs and vaccines are primarily used for the treatment and prevention of smallpox and other orthopoxviral diseases.The antiviral drugs mainly include Teicovirimat,Cidofovir,Brincidofovir,while vaccines mainly use ACAM2000,MVA-BN,and LC16,which have shown effectiveness in treating and preventing Mpox.Currently,Given the absence of a specific drug and a more effective and safer vaccine,these drugs and vaccines can be used in early treatment and prevention to alleviate clinical symptoms caused by the monkeypox virus,reducing the rate of severe disease and mortality.The thesis was discussed in terms of antiviral drugs and vaccines mechanism of action,clinical trials and safety to study the antiviral drugs and vaccines currently used internationally for the treatment of Mpox,with a view to providing reference for the treatment and prevention of Mpox in China.
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