Objective To explore the pharmaceutical care approach of clinical pharmacists in immune-related adverse events caused by toripalimab.Methods A clinical pharmacist conducted a pharmacy checkup on a case in which renal injury,hypothyroidism and skeletal muscle toxicity were detected in a patient treated with toripalimab,and determined that the patient was most likely to have adverse reactions caused by toripalimab through the evaluation of the correlation of the adverse reactions and the analysis of the mechanism.Results A clinical pharmacist assisted the physician in formulating the treatment plan,and conducted full-scale pharmacological monitoring of the patient,achieving good results.Conclusion Clinical pharmacists play an important role in the identification and management of immune-related adverse events,effectively ensure the safety of medication.
关键词
特瑞普利单抗/肾损伤/甲状腺功能减退/骨骼肌毒性/横纹肌溶解症/药品不良反应/药学监护
Key words
toripalimab/renal injury/hypothyroidism/skeletal muscle toxicity/rhabdomyolysis/adverse drug reaction(ADR)/pharmaceutical care
维普
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