中国药物警戒2024,Vol.21Issue(3) :349-351.DOI:10.19803/j.1672-8629.20230594

托珠单抗注射液致过敏性休克1例分析

One case of allergic shock caused by tocilizumab injection

陈杰 张斌 赵俊 张传洲
中国药物警戒2024,Vol.21Issue(3) :349-351.DOI:10.19803/j.1672-8629.20230594

托珠单抗注射液致过敏性休克1例分析

One case of allergic shock caused by tocilizumab injection

陈杰 1张斌 1赵俊 1张传洲1
扫码查看

作者信息

  • 1. 青岛大学附属医院药学部,山东 青岛 266555
  • 折叠

摘要

目的 分析托珠单抗注射液致过敏性休克的特点,为临床合理用药提供参考.方法 报道1例儿童使用托珠单抗导致过敏性休克的案例,通过文献回顾托珠单抗导致过敏性休克的情况,并分析原因及防治措施.结果 根据患者的临床表现及药物与用药时间的关联性,考虑托珠单抗导致过敏性休克,患者经有效抗过敏治疗后,过敏性休克症状得到缓解.结论 临床应用托珠单抗应警惕过敏性休克等过敏情况,对严重过敏患者应禁止使用.

Abstract

Objective To analyze the characteristics of anaphylactic shock induced by tocilizumab injection in order to provide reference for clinical safe and rational drug use.Methods One case of anaphylactic shock caused by tocilizumab was analyzed.The related literature was reviewed while the causes,prevention and treatment of such adverse drug reactions were analyzed.Results According to the clinical manifestations of the patient and the correlation between the drug and the time of administration,this case of anaphylactic shock was considered to have been caused by tocilizumab.The symptoms of anaphylactic shock were relieved after effective anti-allergic treatment.Conclusion Clinicians should be wary of anaphylactic shock and other allergic conditions related to the use of tocilizumab,which should not be used in allergic patients.

关键词

托珠单抗/注射液/过敏性休克/药品不良反应/儿童

Key words

tocilizumab/injection/allergic shock/adverse drug reaction/children

引用本文复制引用

出版年

2024
中国药物警戒
国家药品监督管理局药品评价中心(国家药品不良反应监测中心)

中国药物警戒

CSTPCD
影响因子:1.105
ISSN:1672-8629
参考文献量18
段落导航相关论文