Objective To analyze the characteristics of anaphylactic shock induced by tocilizumab injection in order to provide reference for clinical safe and rational drug use.Methods One case of anaphylactic shock caused by tocilizumab was analyzed.The related literature was reviewed while the causes,prevention and treatment of such adverse drug reactions were analyzed.Results According to the clinical manifestations of the patient and the correlation between the drug and the time of administration,this case of anaphylactic shock was considered to have been caused by tocilizumab.The symptoms of anaphylactic shock were relieved after effective anti-allergic treatment.Conclusion Clinicians should be wary of anaphylactic shock and other allergic conditions related to the use of tocilizumab,which should not be used in allergic patients.
关键词
托珠单抗/注射液/过敏性休克/药品不良反应/儿童
Key words
tocilizumab/injection/allergic shock/adverse drug reaction/children