Objective To analyze the adverse reactions-acute transient depression-caused by a quadruple anti-Helicobacter pylori regimen,and to provide reference for early detection and prompt clinical interventions in such cases.Methods Analysis was made of the clinical data on a 29-year-old female patient who underwent a quadruple regimen(amoxicillin,clarithromycin,pantoprazole,and bismuth potassium citrate)because of acute transient depression caused by Helicobacter pylori infection.Results The transient acute depression was considered to have been triggered by the combined use of four anti-Helicobacter pylori drugs.Evidence-based medicine suggested that clarithromycin was the drug most likely to induce acute transient depression.Conclusion Healthcare providers should vigilantly observe patients for emotional fluctuations during the administration of pharmaceutical interventions for the complete eradication of H.pylori infection.In the event of acute transient depression,it is imperative to promptly discontinue the medication to forestall the worsening of symptoms.
关键词
克拉霉素/阿莫西林/泮托拉唑/枸橼酸铋钾/幽门螺杆菌/抑郁症/药品不良反应
Key words
clarithromycin/amoxicillin/pantoprazole/bismuth potassium citrate/helicobacter pylori/depression/adverse drug reactions
维普
万方数据