中国药物警戒2024,Vol.21Issue(3) :355-360.DOI:10.19803/j.1672-8629.20220687

硫磺熏蒸对白芷质量的影响及产地替代加工方式探讨

Effect of sulfur fumigation on quality of Angelica dahurica and alternative processing methods in producing areas

王常顺 王晓蕾 段吉平 袁浩 刘永利 赵丁
中国药物警戒2024,Vol.21Issue(3) :355-360.DOI:10.19803/j.1672-8629.20220687

硫磺熏蒸对白芷质量的影响及产地替代加工方式探讨

Effect of sulfur fumigation on quality of Angelica dahurica and alternative processing methods in producing areas

王常顺 1王晓蕾 2段吉平 2袁浩 2刘永利 2赵丁3
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作者信息

  • 1. 河北省药品医疗器械检验研究院,国家药品监督管理局中药材质量监测评价重点实验室,河北石家庄,050227;河北医科大学生药学教研室,河北石家庄,050017
  • 2. 河北省药品医疗器械检验研究院,国家药品监督管理局中药材质量监测评价重点实验室,河北石家庄,050227
  • 3. 河北医科大学生药学教研室,河北石家庄,050017
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摘要

硫磺熏蒸作为一种中药材产地加工养护方法,具有治虫防霉、保持色泽光鲜、加速中药材干燥等功效.然而硫磺熏蒸也会导致中药材活性成分含量降低、转化成新的化合物,二氧化硫残留量及重金属与有害元素含量升高,导致药效降低、不良反应增加和健康风险.本文在现有文献的基础上归纳总结硫磺熏蒸对白芷质量的影响及产地加工方式探讨,为白芷的质量控制提供参考.

Abstract

Sulfur fumigation,as a processing and preservation method of traditional Chinese medicine in producing areas,is capable of insect control,mildew prevention,maintenance of bright color and acceleration of drying of traditional Chinese medicine.However,sulfur fumigation can also reduce the content of active ingredients in Chinese medicinal materials and transform them into new compounds while increasing the content of sulfur dioxide residue,heavy metals and harmful elements,which may reduce the efficacy but increase safety risks.Based on the literature available,this paper summarizes the impact of sulfur fumigation on the quality of Angelica dahurica and studies the processing methods in producing areas in order to provide reference for quality control of Angelica dahurica.

关键词

硫磺熏蒸/白芷/活性差异/质量控制/产地加工/药效/不良反应

Key words

sulfur fumigation/A.dahurica/activity difference/quality control/processing in the producing area/pharmacological effect/adverse reactions

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基金项目

河北省重点研发计划(21372502D)

出版年

2024
中国药物警戒
国家药品监督管理局药品评价中心(国家药品不良反应监测中心)

中国药物警戒

CSTPCD
影响因子:1.105
ISSN:1672-8629
参考文献量40
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