Objective To explore types of toxins,poisoning features and future utilization in the areas of medicine and biology,provide a new perspective for an objective understanding of Amanita safety,as well as references for further rational development and security applications of Amanita.Methods Based on the relevant literature in China and abroad,the present study of poisoning features,exploitation and utilization of toxins in Amanita were categorized,analyzed and summarized.Results Amanita mainly contains toxic components such as peptides,amino acids,and alkaloids,which are affected by the species,the application site and a variety of factors,resulting in a great difference in the composition and content.Main poisoning features of Amanita are gastrointestinal symptomsand acute liver and kidney injury.Meantime,these toxic components also have development and utilization value in the development of antibacterial,anti-tumor,anti-inflammatory and other drugs and play important roles in life science researches.Conclusion Amanita has important development value,toxic compositions types and mechanisms and safe dosages of Amanita are clarified to provide reference for the development and safe clinical utility.
关键词
鹅膏菌/鹅膏毒肽/毒性成分/中毒特征/剧毒/资源开发
Key words
Amanita/amatoxin/toxins/poisoning features/virulent/resource development
维普
万方数据