Objective To investigate the current management level of compound glycyrrhiza oral solution,and to offer recommendations for improvement.Methods Related literature was retrieved from CNKI,Wanfang,VIP,the website of the FDA of the United States,and the official websites of NMPA and provincial drug regulatory agencies of China before being summarized and analyzed.Results There were some problems with this solution,such as unstable preparation processes,incomplete standards for content determination,ambiguous instructions,and complicated ADRs during the use of compound glycyrrhiza oral solution in China.Conclusion It is recommended that ways to regulate similar drugs at home and abroad be referred to to optimize the regulations of CGOS,the targets of marketing and processes be standardized for enterprises,health care providers be better trained and related knowledge be made more accessible.