Objective To study the ancient Mongolian Medical literature from the perspective of pharmacovigilance,explain the theoretical connotation of Mongolian Medicine pharmacovigilance,and provide a reference for further research on the safety evaluation and pharmacovigilance of Mongolian Medicine.Methods By combing through over 40 classic works of Mongolian Medicine and historical documents since the 4th century,the content related to pharmacovigilance was excavated,and the toxicity theory and characteristics of safe and rational drug use in Mongolian Medicine were analyzed.Results The study found that Mongolian Medicine attaches great importance to the duality of drugs,which means that drugs can bring harm to the human body while treating diseases.The Mongolian Medicine pharmacovigilance is mainly reflected in the following aspects:the understanding of toxicity,detoxification of poisoning,dietary taboos,living taboos,physical taboos,disease taboos,and other medication taboos;methods of reducing toxicity such as compatibility and processing;principles for controlling drug dosage and treatment duration;as well as the characteristics of dosage forms.Conclusion Mongolian people have a long history of understanding and using"toxicity",coupled with the theoretical characteristics of Mongolian Medicine and clinical medication differences,the practice of safe and rational drug use is rich and unique.Exploring the scientific connotation of Mongolian Medicine pharmacovigilance has practical and far-reaching significance for guiding the rational use of Mongolian Medicine in modern clinical practice and inheriting traditional medicine.
关键词
蒙药/古籍/药物警戒/药品不良反应/毒/用药禁忌/配伍/炮制
Key words
Mongolian Medicine/ancient books/pharmacovigilance/adverse drug reaction/toxicity/compatibility/processing
维普
万方数据