Objective To analyze the marketed combination antihypertensive drugs and the rationality of their components,explore their composition and assess their efficacy so as to provide references for the development and innovation of combination antihypertensive drugs.Methods The marketed compound drug combinations and approved drug combination therapy regimens were analyzed and summarized by searching domestic and foreign literature.Results With multiple mechanisms of action,compound antihypertensive drugs could improve drug compliance,reduce cardiovascular risks,and lower overall treatment cost.Conclusion Compound antihypertensive drugs have unique advantages in the treatment of hypertension.Compound drugs are also the best choice for the treatment of hypertension and concomitant diseases,which will provide a new impetus for the development of compound drugs in the future.