Objective To explore the clinical characteristics and mechanism of adverse drug reactions caused by ceftriaxone in children with immune hemolytic anemia.Methods Two cases of ceftriaxone sodium induced adverse reactions in children with immune hemolytic anemia and the correlations with adverse reactions were analyzed.Results Correlation analysis showed that both cases of hemolytic anemia were caused by ceftriaxone sodium,which was immediately discontinued and the patients were discharged after blood transfusion and glucocorticoid treatment.Conclusion Clinicians should pay attention to the risk of adverse reactions of ceftriaxone-induced immune hemolytic anemia in clinical practice.Rapid identification and appropriate immunological diagnosis and treatment can facilitate the prognosis of patients.
关键词
头孢曲松/免疫性溶血性贫血/腹痛/过敏性休克/药品不良反应/抗头孢曲松抗体/血清学检测/儿童
Key words
Ceftriaxone/Immune Hemolytic Anemia/Abdominal Pain/Anaphylactic Shock/Adverse Drug Reaction/Anti-Ceftriaxone Antibody/Serological Test/Children
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