摘要
苦参既能清湿热、利尿杀虫,又能祛风邪而止痒,在临床应用较为广泛.苦参化学成分复杂多样,是其发挥药理活性的内在基础,且现代药理学研究发现,苦参在抗炎抗菌、抗心律失常、催眠镇静、抗肿瘤、降血糖等多个领域皆发挥一定的药理学效果,但具体作用机制尚未十分明确.本文主要对苦参的化学成分、药理作用及临床应用整理概括作一论述,旨在为中药苦参在今后的临床试验研究中提供充分的科学依据.
Abstract
Lightyellow sophora root can not only clear dampness-heat,diuretic kill insects,but also dispel wind evil and relieve itching,which is widely used in clinic.The chemical composition of lightyellow sophora rootis complex and diverse,which is the intrinsic basis of its pharmacological activity.In addition,modern pharmacological studies have found that lightyellow sophora root has certain pharmacological effects in anti-inflammatory and antibacterial,anti-arrhythmia,hypnotic and sedative,anti-tumor,hypoglycemic and other fields,but the exact mechanism of action is not well understood.In this paper,the chemical composition,pharmacological action and clinical application of lightyellow sophora root are summarized in order to provide sufficient theoretical basis for the clinical application and scientific research of Chinese medicine lightyellow sophora root in the future.
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