首页|卡瑞利珠单抗治疗晚期转移性食管鳞癌患者期间应用综合护理干预的效果

卡瑞利珠单抗治疗晚期转移性食管鳞癌患者期间应用综合护理干预的效果

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目的:探讨综合护理干预在卡瑞利珠单抗治疗晚期转移性食管鳞癌患者中的应用效果。方法:选择本院 2021年1月—2022年12月收治的80例晚期转移性食管鳞癌患者为研究对象,按双色球随机法分为对照组和观察组,各40例。所有研究对象采用卡瑞利珠单抗治疗,对照组给予常规护理,观察组给予综合护理,比较两组用药依从性、不良反应发生率及耐药率。结果:干预后,观察组用药依从率高于对照组,不良反应发生率、耐药率低于对照组,差异有统计学意义(P<0。05)。结论:综合护理干预在卡瑞利珠单抗治疗晚期转移性食管鳞癌患者的应用效果良好,可有效提高治疗依从性,降低不良反应发生率及耐药性。
Effect of Comprehensive Nursing Intervention in Patients with Advanced Metastatic Esophageal Squamous Cell Carcinoma During the Carrelizumab Treatment
Objective:To explore the efficacy of comprehensive nursing intervention in patients with advanced metastatic esophageal squamous cell carcinoma during the carrelizumab treatment.Methods:A total of 80 patients with advanced metastatic esophageal squamous cell carcinoma admitted to our hospital from January 2021 to December 2022 were selected as the research objects,and were divided into control group and observation group according to the double chromosphere random method,with 40 patients in each group.All the subjects were treated with carrelizumab,while the control group was given routine nursing,and the observation group was given comprehensive nursing.The medication compliance,incidence of adverse reactions and drug resistance rate were compared between the two groups.Results:After intervention,the medication compliance rate of the observation group was higher than that of the control group,the incidence of adverse reactions and drug resistance rate were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion:The application effect of comprehensive nursing intervention in patients with advanced metastatic esophageal squamous cell carcinoma treated with carrelizumab is good,which can effectively improve the treatment compliance and reduce the incidence of adverse reactions and drug resistance.

Comprehensive nursingCaryllisuzumabAdvanced metastatic esophageal squamous cell carcinoma

许孟、芦夏、李芳、周玲

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河南省南阳市中心医院CT影像诊断科,河南 南阳 473000

综合护理干预 卡瑞利珠单抗 晚期转移性食管鳞癌

河南省医学科技攻关联合共建项目

LHGA20200768

2024

中国药物滥用防治杂志
中国药物滥用防治协会 军事医学科学院毒物药物研究所

中国药物滥用防治杂志

影响因子:0.584
ISSN:1006-902X
年,卷(期):2024.(1)
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