目标策略下的分级干预在乌司他丁治疗急性胰腺炎患者期间的应用效果
Application Effect of Graded Intervention Under Target Strategy During the Ulinastatin Treatment Period in Patients with Acute Pancreatitis
温梦丽 1苗晶晶 1秦宝山1
作者信息
- 1. 河南中医药大学第五临床医学院/郑州人民医院,河南 郑州 450000
- 折叠
摘要
目的:探讨目标策略下的分级干预在急性胰腺炎患者乌司他丁治疗期间的应用效果.方法:选取2021年1月—2023 年 8 月采用乌司他丁治疗的86 例急性胰腺炎患者,依据随机数字表法分为对照组(43 例,实施分级干预)和观察组(43 例,实施目标策略下的分级干预),均持续干预 2 周.比较两组恢复时间、病情危重程度[急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)]、并发症发生情况.结果:观察组住院时间、腹痛缓解时间短于对照组(P<0.05);观察组干预 2 周时APACHEⅡ评分低于对照组(P<0.05);观察组干预期间并发症总发生率低于对照组(P<0.05).结论:急性胰腺炎患者乌司他丁治疗期间应用目标策略下的分级干预效果显著,可缩短患者恢复进程,降低患者病情危重程度和并发症发生情况.
Abstract
Objective:To explore the application effect of graded interventions under target strategies during the ulinastatin treatment period in patients with acute pancreatitis.Methods:A total of 86 patients with acute pancreatitis treated with ulinastatin in hospitals from January 2021 to August 2023 were selected and randomly divided into a control group(43 patients,implementing graded intervention)and an observation group(43 patients,implementing graded intervention under the target strategy)using a random number table method,both of which were continuously intervened for 2 weeks.The recovery time,severity of illness[Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ)]and complications were compared between the two groups.Results:The hospitalization time and abdominal pain relief time in the observation group were shorter than those in the control group(P<0.05).At 2 weeks of intervention,the APACHEⅡ score in the observation group was lower than that in the control group(P<0.05).The total incidence of complications during the intervention period in the observation group was lower than that in the control group(P<0.05).Conclusion:The application of graded intervention under the target strategy during the ulinastatin treatment period in patients with acute pancreatitis has a significant effect,which can shorten the patient's recovery process,reduce the severity of the patient's condition,and reduce the incidence of complications.
关键词
目标策略/分级干预/急性胰腺炎/乌司他丁Key words
Target strategy/Graded intervention/Acute pancreatitis/Ulinastatin引用本文复制引用
基金项目
河南医学科技公关联合共建项目(LHGJ20220780)
出版年
2024
NETL
NSTL
万方数据