Study on the effect of Shenqi Qiangxin Decoction in the Treatment of Chronic Heart Failure with Qi and Yin Deficiency and Blood Stasis and Water Stasis
Objective:To study the application value of Shenqi Qiangxin Decoction combined with conventional western medicine in the treatment of patients with chronic heart failure(CHF)of Qi and Yin deficiency and blood stasis and water stasis.Methods:A total of 106 patients with CHF of Qi and Yin deficiency and blood stasis and water stasis who were admitted to Lushan Jianmin Hospital from March 2019 to January 2021 were selected as the study subjects,and the patients were divided into study group and control group according to the method of random number table,with 53 patients in each group.The control group was treated with western medicine,while the study group was treated with Shenqi Qiangxin Decoction combined with western medicine.The clinical efficacy,cardiac function[cardiac index(CI),stroke output(SV),left ventricular ejection fraction(LVEF)],total score of TCM syndromes,6-minute walking distance test(6MWT),vascular endothelial function index[endothelin-1(ET-1),angiotensin Ⅱ(ANGⅡ),nitric oxide synthase(NOS)]and adverse events were compared between the two groups.Results:The total effective rate of the study group was 94.33%,which was higher than 79.25%of the control group(P<0.05).After treatment,the CI,LVEF,SV and NOS of the study group were higher than those of the control group,the total score of TCM syndromes,ET-1,and ANGⅡwere lower than those of the control group,and the distance of 6 MWT was far higher than that of the control group(P<0.05).The total incidence of adverse events in the study group was 9.80%,which was lower than 26.53%in the control group(P<0.05).Conclusion:Shenqi Qiangxin Decoction combined with conventional western medicine has a significant effect on the treatment of CHF of Qi and Yin deficiency and blood stasis and water stasis,which can restore and improve blood circulation,recover patients'heart function.Meanwhile,it help to enhance exercise endurance,reduce clinical symptoms,and reduce the risk of adverse events.
Shenqi Qiangxin DecoctionQi and Yin blood deficiency combined with blood stasis and water stasisChronic heart failure6-min walking distance test
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