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某精神专科医院门诊Z类药物处方情况调查分析

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目的:分析某精神专科医院门诊Z类药物的处方情况,发现该类药物滥用/依赖风险信号,找出影响该类药物滥用/依赖的相关因素.方法:回顾性研究2021年6月—2022年5月门诊处方Z类药物的人群.建立用药风险信号识别要点,筛查出疑似滥用/依赖人群,应用调查问卷进行电话回访判断其是否药物滥用/依赖,并对滥用/依赖人群进行分析.结果:筛查出551例疑似滥用/依赖的患者,符合药物依赖/依赖诊断的患者30例.单因素分析显示,是否经历重大事件、依从性、家人对药品合理管理、知晓Z类药物有依赖风险及随诊是该类患者发生药物依赖的影响因素(P<0.05).二元logistic回归分析显示,未经历重大事件和用药依从性好可能是Z类药物依赖的保护因素,家人对药品不合理管理和不随诊可能是Z类药物依赖的危险因素(P<0.05).结论:Z类药物存在一定程度的滥用/依赖,大多患者对该类药物认识不足,需进一步加强健康教育和用药行为干预,以减少Z类药物的滥用/依赖.
Investigation and Analysis on the Prescription of Z-type Drugs in Outpatients of a Psychiatric Hospital
Objective:To analyze the prescriptions of Z-type drugs in the outpatient department of a psychiatric hospital,to find out the risk signals of drug abuse/dependence,and to find out the related factors affecting drug abuse/dependence.Method:A retrospective study was conducted on the population of outpatient prescriptions of Z-type drugs from June 2021 to May 2022.The key points of drug risk signal identification were establish to screen out the suspected abuse/dependence population,and the questionnaire was used to conduct telephone follow-up to determine whether they were drug abuse/dependence,and the abuse/dependence population was analyzed.Results:A total of 551 patients with suspected abuse/dependence were screened,and 30 patients were diagnosed with drug dependence/dependence.Univariate analysis showed that whether experiencing major events,compliance,reasonable family management of drugs,awareness of the risk of dependence on Z-type drugs and follow-up were the influencing factors of drug dependence in such patients(P<0.05).Binary logistic regression analysis showed that not experiencing major events and good medication compliance may be protective factors for Z-type drugs dependence,and unreasonable family management of drugs and non-follow-up may be risk factors for Z-type drugs dependence(P<0.05).Conclusion:There is a certain degree of abuse/dependence of Z-type drugs,and most patients have insufficient understanding of these drugs.It is necessary to further strengthen health education and medication behavior intervention to reduce the abuse/dependence of Z-type drugs.

Z-type drugsAbuseDependencyInsomnia

支晓慧、李霞、王晓、孙波、王文文、刘召英

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临沂市精神卫生中心药学部,山东 临沂 276005

山东省药品不良反应监测中心,山东 济南 250013

临沂市精神卫生中心精神科,山东 临沂 276005

Z类药物 滥用 依赖 失眠

山东省药物滥用监测哨点研究课题

药械化-2022-SDADRKY08

2024

中国药物滥用防治杂志
中国药物滥用防治协会 军事医学科学院毒物药物研究所

中国药物滥用防治杂志

影响因子:0.584
ISSN:1006-902X
年,卷(期):2024.30(4)
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