Objective:To analyze the characteristics of 1595 cases of adverse drug reactions(ADR)reported in order to provide reference for clinical safe medication.Methods:A total of 1595 cases of data reported by a hospital to the adverse drug reaction monitoring and management system were collected and retrospectively analyzed from the aspects of report type,patient gender,age,route of administration,drug dosage form,involving system-organs,types of drugs with ADR,types of antibacterial drugs,and varieties of traditional Chinese medicine injections.Results:The proportion of ADR in women(61.95%)was higher than that in men(38.05%),and patients over 50 years old(71.48%)were prone to ADR.The incidence of ADR was the highest in intravenous drip(86.02%),and the organ or system damage caused by ADR was mainly in skin and skin accessory diseases,with a total of 730 cases(29.86%).603 cases(37.81%)of antibiotics and 205 cases(12.85%)of traditional Chinese medicine injection were the most likely to cause ADR.The most common antibiotics causing ADR were quinolones(238 cases),followed by cephalosporins(144 cases).The most common TCM injection causing ADR was Shenmai injection(138 cases).Conclusion:ADR is related to gender,age,route of administration,drug type and other factors.It is necessary to strengthen the monitoring of anti-infection,traditional Chinese medicine injection and other drugs,improve the clinical rational drug use rate,reduce the occurrence of adverse drug reactions,and ensure the safety of patients.
Adverse drug reactionsAntimicrobial agentsChinese medicine injectionRational drug use
NETL
NSTL
万方数据
