首页|氨溴索注射液聚集性药品不良事件分析及预防措施

氨溴索注射液聚集性药品不良事件分析及预防措施

扫码查看
目的:分析氨溴索注射液发生聚集性药品不良事件的原因.方法:回顾性分析我院在2023年5月10日—15日期间 6 例氨溴索注射液聚集性药品不良事件,对患者基本信息、用药信息、不良反应症状及转归情况进行分析.结果:6例病例集中在儿科病区,患者均为儿童,其基础疾病为支气管肺炎及支气管炎;使用溶媒均为5%葡萄糖注射液;发生不良反应日期,1 例发生在使用氨溴索注射液当日,其余 5 例发生在连续使用氨溴索注射液 2~3 日;静脉滴注使用盐酸氨溴索注射液前后均有冲洗输液器;患者临床主要表现为呕吐、腹痛等消化系统反应.结论:聚集性不良反应是药师监测不良反应的重要信号,药学部根据此次聚集性药品不良事件制定相应的预防措施,为聚集性药品不良反应的早期预警、快速反馈、及时处理提供实践依据.
Analysis and Preventive Measures of Cluster Adverse Drug Events of Ambroxol Injection
Objective:To explore and analyze the causes of the cluster adverse drug events of ambroxol injection.Methods:Retrospective analysis of 6 cases of cluster adverse drug events of ambroxol injection in our hospital from May 10 to May 15,2023.The basic information,medication information,adverse reaction symptoms and prognosis of patients were analyzed..Results:The 6 cases were concentrated in the pediatric ward,and the patients were all children.The basic diseases were bronchial pneumonia and bronchitis.The solvent was 5%glucose injection;on the date of adverse reactions,1 case occurred on the day of using ambroxol injection,and the remaining 5 cases occurred on 2-3 days of continuous use of ambroxol injection.Before and after intravenous infusion of ambroxol injection,there were irrigation infusion sets.The main clinical manifestations of the patients were vomiting,abdominal pain and other digestive system reactions.Conclusion:Cluster adverse drug events are important signals for pharmacists to monitor adverse reactions.The pharmacy department formulates corresponding preventive measures according to the cluster adverse drug events,and provides practical basis for early warning,rapid feedback and timely treatment of cluster adverse drug events.

Ambroxol injectionCluster adverse drug eventsPreventive measures

郭晓松、冯雪、位宁、柴清军

展开 >

河南省漯河市中医院药学部,河南漯河 462000

氨溴索注射液 聚集性药品不良反应事件 预防措施

2024

中国药物滥用防治杂志
中国药物滥用防治协会 军事医学科学院毒物药物研究所

中国药物滥用防治杂志

影响因子:0.584
ISSN:1006-902X
年,卷(期):2024.30(4)
  • 8