Evaluation and Analysis of Clinical Application of Tigecycline in a Tertiary Hospital from 2021 to 2023
Objection:To retrospectively analyze the information of patients who used tigecycline in the People's Hospital of Qiandongnan Miao and Dong Autonomous Prefecture of Guizhou Province from November 2021 to May 2023,and to evaluate and analyze the rationality,effectiveness and safety of the drug,so as to provide reference for clinical medication.Methods:The PASS system was used to analyze the basic information of patients using tigecycline,including age,gender,department,clinical diagnosis,bacterial drug sensitivity test and drug regimen,combined use of other antibiotics.By consulting the patient's medical record data,treatment process and adverse drug reaction records,the reasonable rate,effective rate and safety rate of tigecycline use were analyzed and calculated.Results:A total of 38 patients were treated with tigecycline in the hospital in the past two years,the reasonable rate of use was 23.68%,the effective rate of treatment was 23.68%,and the incidence of adverse drug reactions was 13.16%.Conclusion:The rational use rate and effective rate of tigecycline in this hospital are low.The pharmaceutical department should strengthen the training of the principles,indications,usage and dosage and safety of tigecycline in clinical practice,so as to improve the rationality and effectiveness of drug use and reduce the risk of adverse drug reactions.
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