首页|右美托咪定超前镇痛对腺样体/扁桃体切除术患儿麻醉效果的影响

右美托咪定超前镇痛对腺样体/扁桃体切除术患儿麻醉效果的影响

扫码查看
目的:探讨右美托咪定超前镇痛对腺样体/扁桃体切除术幼儿麻醉苏醒质量、血流动力学、苏醒期躁动和疼痛强度的影响.方法:选取本院 2021 年 1 月—2022 年 10 月收治的 84 例择期行全麻腺样体/扁桃体切除术患儿,根据随机数字表法分为常规麻醉组和超前镇痛组,每组42例.比较两组麻醉苏醒质量[拔管时间、苏醒时间、滞留麻醉恢复室(PACU)时间]、麻醉诱导前20 min、诱导插管后20 min、入PACU后10 min的血流动力学指标[心率(HR)、平均动脉压(MAP)]、苏醒期躁动情况[苏醒期躁动评分表(PAED)]、术后疼痛强度[Wong-bank面部表情量表法(FPS)]、不良反应.结果:超前镇痛组拔管时间、苏醒时间、PACU滞留时间短于常规麻醉组(P<0.05);诱导插管后 20 min、入PACU后10 min,超前镇痛组HR、MAP均低于常规麻醉组(P<0.05);苏醒期,超前镇痛组PAED评分、FPS评分低于常规麻醉组(P<0.05);麻醉苏醒后,超前镇痛组不良反应发生率为19.05%,明显低于常规麻醉组的4.76%(P<0.05).结论:右美托咪定超前镇痛应用于腺样体/扁桃体切除术幼儿,有利于稳定患儿血流动力学,苏醒质量更高,可减轻麻醉苏醒期躁动和疼痛强度,且不良反应较少,安全性较高,有望成为幼儿全麻诱导的安全有效方案.
Effects of Dexmedetomidine Preemptive Analgesia on Anesthesia in Children Undergoing Adenoidectomy/Tonsillectomy
Objective:To investigate the effects of dexmedetomidine preemptive analgesia on the quality of anesthesia,hemodynamics,restlessness during recovery,and pain intensity in children undergoing adenoidectomy/tonsillectomy.Methods:Eighty-four children undergoing elective adenoidectomy/tonsillectomy under general anesthesia were collected and randomly divided into routine anesthesia group and preemptive analgesia group by random number table method,with 42 cases in each group.The anesthesia recovery quality[extubation time,recovery time,stay in the anesthesia recovery room(PACU)time],hemodynamic parameters[heart rate(HR),mean arterial pressure(MAP)]before 20 minutes of anesthesia induction,after 20 minutes of induction and intubation,after 10 minutes of admission to PACU,restlessness during recovery(PAED),postoperative pain intensity[(Wong bank facial expression scale(FPS)],and adverse reactions were compared between the two groups.Results:The extubation time,recovery time,and PACU retention time in the preemptive analgesia group were shorter than those in the routine anesthesia group(P<0.05);HR and MAP in the preemptive analgesia group were lower than those in the conventional anesthesia group after 20 minutes of induction and intubation and after 10 minutes of admission to PACU(P<0.05);during the recovery period,the scores of PAED and FPS in the preemptive analgesia group were lower than those in the routine anesthesia group(P<0.05);after awakening from anesthesia,the incidence of adverse reactions in the preemptive analgesia group was 19.05%,which was significantly lower than 4.76%in the routine anesthesia group(P<0.05).Conclusion:The application of dexmedetomidine preemptive analgesia in children undergoing adenoidectomy/tonsillectomy is beneficial for stabilizing the hemodynamics of the children,improving the quality of recovery,reducing agitation and pain intensity during anesthesia recovery,with fewer adverse reactions and higher safety.It is expected to become a safe and effective regimen for general anesthesia induction in children.

DextrmetomidinePreemptive analgesiaAdenoidectomy/tonsillectomyConvalescent agitation

王艳新、樊军晓、孙得月、谢爽

展开 >

南阳张仲景医院麻醉科,河南 南阳 473000

右美托咪定 超前镇痛 腺样体/扁桃体切除术 苏醒期躁动

2024

中国药物滥用防治杂志
中国药物滥用防治协会 军事医学科学院毒物药物研究所

中国药物滥用防治杂志

影响因子:0.584
ISSN:1006-902X
年,卷(期):2024.30(5)