Effects of Dexmedetomidine Preemptive Analgesia on Anesthesia in Children Undergoing Adenoidectomy/Tonsillectomy
Objective:To investigate the effects of dexmedetomidine preemptive analgesia on the quality of anesthesia,hemodynamics,restlessness during recovery,and pain intensity in children undergoing adenoidectomy/tonsillectomy.Methods:Eighty-four children undergoing elective adenoidectomy/tonsillectomy under general anesthesia were collected and randomly divided into routine anesthesia group and preemptive analgesia group by random number table method,with 42 cases in each group.The anesthesia recovery quality[extubation time,recovery time,stay in the anesthesia recovery room(PACU)time],hemodynamic parameters[heart rate(HR),mean arterial pressure(MAP)]before 20 minutes of anesthesia induction,after 20 minutes of induction and intubation,after 10 minutes of admission to PACU,restlessness during recovery(PAED),postoperative pain intensity[(Wong bank facial expression scale(FPS)],and adverse reactions were compared between the two groups.Results:The extubation time,recovery time,and PACU retention time in the preemptive analgesia group were shorter than those in the routine anesthesia group(P<0.05);HR and MAP in the preemptive analgesia group were lower than those in the conventional anesthesia group after 20 minutes of induction and intubation and after 10 minutes of admission to PACU(P<0.05);during the recovery period,the scores of PAED and FPS in the preemptive analgesia group were lower than those in the routine anesthesia group(P<0.05);after awakening from anesthesia,the incidence of adverse reactions in the preemptive analgesia group was 19.05%,which was significantly lower than 4.76%in the routine anesthesia group(P<0.05).Conclusion:The application of dexmedetomidine preemptive analgesia in children undergoing adenoidectomy/tonsillectomy is beneficial for stabilizing the hemodynamics of the children,improving the quality of recovery,reducing agitation and pain intensity during anesthesia recovery,with fewer adverse reactions and higher safety.It is expected to become a safe and effective regimen for general anesthesia induction in children.