Effect of Glucocorticoid Combined with Antiviral Drugs in the Treatment of Adolescent Patients with Viral Corneal Endotheliitis
Objective:To investigate the effects of glucocorticoid combined with antiviral therapy on visual recovery and corneal endothelial morphology in adolescent patients with viral corneal endodermatitis.Methods:A total of 126 adolescent patients with viral corneal endotheliitis admitted to Enshi Aier Eye Hospital from February 2021 to February 2024 were selected as the research objects,and they were divided into routine group(63 patients)and observation group(63 patients)according to digital blind sampling method.The conventional group was treated with antiviral therapy,and the observation group was treated with antiviral therapy combined with glucocorticoid therapy.The clinical efficacy,visual acuity recovery and corneal endothelial morphology were compared between the two groups.Results:The total effective rate of the observation group was 95.24%,which was higher than 79.37%of the conventional group(P<0.05).At the same time,the visual acuity of the observation group after treatment was higher than that of the conventional group,and the corneal thickness,corneal cell count and cell diversity variation rate were better than those of the conventional group(P<0.05).Conclusion:Glucocorticoid combined with antiviral therapy can accelerate vision recovery and improve corneal endothelial morphology in adolescent patients with viral keratodermatitis,and the clinical effect is ideal.
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