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柴胡加龙骨牡蛎汤治疗枢机不和型不寐症的临床效果

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目的:探讨柴胡加龙骨牡蛎汤治疗枢机不和型不寐症的临床效果.方法:选择 2021年2月—2022年11月本院收治的不寐症患者 100 例为研究对象,随机分为对照组和观察组,各 50 例.对照组给予右佐匹克隆片治疗,观察组与对照组基础上联合使用柴胡加龙骨牡蛎汤,比较两组临床效果、睡眠质量、日间瞌睡情况及不良反应.结果:治疗 3 d后及治疗1疗程时,观察组总有效率高于对照组(P<0.05);观察组匹兹堡睡眠质量评分、Epworth评分低于对照组(P<0.05);观察组胸满烦惊、心烦气躁、头晕目眩、口干舌燥和小便不利发生率低于对照组(P<0.05).结论:针对枢机不和型不寐症者,使用柴胡加龙骨牡蛎汤临床治疗效果较好,可有效改善患者睡眠质量,降低宿醉感,不良反应少.
Clinical Effect of Chaihu Plus Longgu Muli Decoction in the Treatment of Insomnia of Cardinal Disharmony Type
Objective:To investigate the clinical effect of Chaihu PLus Longgu Muli decoction in the treatment of insomnia of cardinal disharmony type.Methods:A total of 100 patients with insomnia admitted to our hospital from February 2021 to November 2022 were randomly divided into control group and observation group,with 50 patients in each group.The control group was treated with eszopiclone tablets.The observation group and the control group were combined with Chaihu plus Longgu Muli decoction.The sleep quality,daytime sleepiness,adverse reactions and clinical effects were compared between the two groups.Results:After 3 days of treatment and after 1 course of treatment,the Pittsburgh sleep quality score and Epworth score of the observation group were lower than those of the control group(P<0.05);the incidence of thorax restlessness,irritability,dizziness,dry mouth and urine in the observation group was lower than that in the control group(P<0.05);the total effective rate of observation group was higher than that of control group(P<0.05).Conclusion:For insomnia patients with cardinal disharmony type,Chaihu plus Longgu Muli decoction can effectively improve the sleep quality of patients,reduce the sense of hangover,relieve clinical symptoms and ensure the clinical treatment effect.

Chaihu plus Longgu Muli decoctionInsomnia of cardinal disharmony typeInsomniaSleep qualityDaytime drowsiness

陈英哲、张雨芳、吴向东

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平顶山市中医医院脑病科,河南 平顶山 467000

柴胡加龙骨牡蛎汤 枢机不和型 不寐症 睡眠质量 日间瞌睡

2024

中国药物滥用防治杂志
中国药物滥用防治协会 军事医学科学院毒物药物研究所

中国药物滥用防治杂志

影响因子:0.584
ISSN:1006-902X
年,卷(期):2024.30(7)