Comparison of the Effects of Different Intermediate Benzodiazepines in the Treatment of Patients with Alcohol Withdrawal Syndrome
Objective:To study the effect of different effective benzodiazepines in the treatment of alcohol withdrawal syndrome(AWS)and its influence on anxiety and alcohol craving.Methods:A total of 72 patients with AWS admitted to our hospital from August 2021 to August 2023 were selected as the research objects.They were divided into oxazepam group(treated with oxazepam)and lorazepam group(treated with lorazepam)by random number table method,with 36 patients in each group.The clinical efficacy,anxiety,alcohol craving,and adverse reactions were compared between the two groups.Results:After 7 days of treatment,the scores of Alcohol Withdrawal Syndrome Self-rating scale(AWSS),Self-rating Anxiety Scale(SAS)and Hamilton Anxiety Scale(HAMA)in the oxazepam group were lower than those in the lorazepam group,and the differences were statistically significant(P＜0.05).The score of alcohol craving in oxazepam group was lower than that in lorazepam group,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions in the oxazepam group was 2.77%,which was lower than 16.66%in the lorazepam group,and the difference was statistically significant(P＜0.05).Conclusion:Oxazepam is more effective than lorazepam in the treatment of AWS,which can effectively improve the anxiety of AWS patients,reduce the degree of alcohol craving,and has good safety.
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