Investigation of Risk Factors for Hypoglycemia in Neonatal Hemolysis and Analysis of Medication Strategies
Objective:To explore the risk factors and medication strategies of hypoglycemia caused by hemolysis in newborns.Methods:A total of 159 neonatal hemolysis children were admitted to our hospital from February 2022 to February 2024 were selected as the study objects,and they were divided into hypoglycemic group(n=38)and normal blood glucose group(n=121)according to whether the children were complicated with hypoglycemia.General neonatal data and maternal information were collected.The difference of clinical data between hypoglycemia group and normal glycemia group was analyzed by single factor.The risk factors of hypoglycemia in neonatal hemolysis were analyzed by Logistic analysis.Results:Single factor results showed that the proportion of children with birth weight＜2500 g,asphyxia,hypoxemia,hypothermia and gestational age＜37 weeks in hypoglycemia group was higher than that in normal blood glucose group,and the proportion of maternal gestational diabetes mellitus was higher than that in normal blood glucose group(P＜0.05).Logistic results showed that birth weight＜2500g,asphyxia,hypoxemia,hypothermia,gestational age＜37 weeks and maternal gestational diabetes mellitus were all risk factors for neonatal hemolytic hypoglycemia(P＜0.05).Conclusion:The risk factors of neonatal hemolysis hypoglycemia include birth weight＜2500g,asphyxia,hypoxemia,hypothermia,gestational age＜37 weeks and maternal gestational diabetes mellitus.We should clinically monitor the blood glucose of hemolytic newborns early and continuously to detect abnormal blood glucose fluctuations in time.Meanwhile,we can give glucose solution intravenously and pay close attention to the electrolyte balance of children.
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