Effect of Atorvastatin Calcium Tablets Combined with Aspirin in the Treatment of Cerebral Thrombosis
Objective:To investigate the effect of atorvastatin calcium tablets combined with aspirin in the treatment of cerebral thrombosis.Methods:A retrospective analysis of 73 patients with cerebral thrombosis who were treated in our hospital from January 2020 to April 2022 was conducted.Patients were divided into experimental group(n=39)and control group(n=34)according to different treatment regimens.The control group was treated with aspirin alone,and the experimental group was treated with atorvastatin calcium tablets on the basis of the control group.The therapeutic effects of the two groups were compared.Results:The clinical effective rate of the experimental group was higher than that of the control group(P＜0.05).After treatment,the carotid plaque area,intima-media thickness,platelet aggregation rate and NIHSS score in the experimental group were lower than those in the control group(P＜0.05).After treatment,total cholesterol(TC),triglyceride(TG)and low density lipoprotein cholesterol(LDL-C)in the experimental group were lower than those in the control group,and high density lipoprotein cholesterol(HDL-C)was higher than that in the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion:Atorvastatin calcium tablets combined with aspirin is effective and safe in the treatment of cerebral thrombosis,which is better than aspirin alone.
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