Effect of Cefazolin Sodium Pentahydrate During Rehabilitation After Tension-free Hernia Repair
Objective:To explore the effect of sulfadiazine combined with cefazolin sodium pentahydrate on incision infection in patients with tension-free hernia repair.Methods:A retrospective analysis was made on the clinical data of 60 patients with tension-free hernia repair admitted to the Department of Surgery,Shaoyuan Health Center,Jiyuan City from June 2020 to June 2023.The patients were divided into control group and study group according to the treatment method,with 30 cases in each group.The study group was treated with sulfadiazine combined with cefazolin sodium pentahydrate,while the control group was only treated with sulfadiazine.The incision healing efficiency,incision infection rate,incision pain,inflammation index and incision discomfort were compared between the two groups.Results:The effective rate of wound healing in the study group was higher than that in the control group,and the incision infection rate was lower than that in the control group(P＜0.05).The pain scores of the study group were lower than those of the control group at 1 d,3 d and 7 d after operation(P＜0.05).The levels of serum IL-6,TNF-α and CRP in the study group were lower than those in the control group at 1 d,3 d and 7 d after operation(P＜0.05).The incidence of incision discomfort in the study group was lower than that in the control group(P＜0.05).Conclusion:Sulfadiazine combined with cefazolin sodium pentahydrate can promote incision healing in patients with tension-free hernia repair,prevent incision infection,reduce incision pain,inhibit inflammatory response,and have less incision discomfort.It is worthy of clinical application.
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