Effect of Estradiol Valerate Tablets Combined with Biofeedback Electrical Stimulation in the Treatment of Female Pelvic Floor Dysfunction
Objective:To explore the effect of estradiol valerate tablets treatment on pelvic floor function in female patients with pelvic floor dysfunction diseases.Methods:A total of 92 female patients with pelvic floor dysfunction who were treated in our hospital from January 2022 to December 2023 were selected as subjects.They were randomly divided into reference group(46 patients)and study group(46 patients)by drawing lots.The reference group was treated with biofeedback electrical stimulation,and the study group was treated with biofeedback electrical stimulation combined with estradiol valerate tablets.The therapeutic effect,pelvic floor dysfunction questionnaire(PFDI-20),pelvic floor function,estradiol(E2)and bone formation markers were compared between the two groups.Results:The total effective rate of treatment in the study group was higher than that in the reference group(P＜0.05).The PFDI-20 score of the study group at 1 month,2 months and 3 months after treatment was lower than that of the study group,and the total effective rate of the study group was higher than that of the reference group(P＜0.05).The average value of typeⅡ muscle fiber and the maximum value of type Ⅰ muscle fiber in the study group were higher than those in the reference group(P＜0.05).The E2 level of the study group was higher than that of the reference group at 1 month,2 months and 3 months after treatment(P＜0.05).After treatment,the levels of alkaline phosphatase(ALP)and osteocalcin(OC)in the study group were higher than those in the reference group(P＜0.05).Conclusion:Estradiol valerate tablets can effectively improve the pelvic floor function of female patients with pelvic floor dysfunction,improve the levels of E2,ALP and OC,and the treatment effect is significant.
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