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磺胺嘧啶银联合湿润烧伤膏治疗Ⅱ度烧伤的效果

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目的:探讨磺胺嘧啶银联合湿润烧伤膏治疗Ⅱ度烧伤的效果.方法:回顾性分析2022年1月—2023年12月医院治疗的 100 例Ⅱ度烧伤患者临床资料,根据随机数字表法将患者分为对照组和观察组,每组50 例.对照组接受湿润烧伤膏治疗,观察组接受磺胺嘧啶银联合湿润烧伤膏治疗,比较两组创面愈合情况(创面愈合时间、肉芽生长时间、瘢痕发生率)、创面分泌物情况、疼痛程度、不良反应.结果:观察组创面愈合时间、肉芽生长时间短于对照组,瘢痕发生率低于对照组,差异有统计学意义(P<0.05);观察组整体创面分泌物少于对照组、整体疼痛程度轻于对照组(P<0.05).两组治疗期间不良反应发生率比较,差异无统计学意义(P>0.05).结论:对Ⅱ度烧伤患者使用磺胺嘧啶银联合湿润烧伤膏治疗可加速创面愈合、肉芽生长,减少创面分泌物并减轻疼痛感,且联合治疗不增加不良反应,安全性好.
Effect of Silver Sulfadiazine Combined with Moist Exposed Burn Ointment in the Treatment of Second Degree Burn
Objective:To investigate the effect of silver sulfadiazine combined with moisture exposed burn ointment in the treatment of second degree burn.Methods:The clinical data of 100 patients with second degree burns treated in the hospital from January 2022 to December 2023 were retrospectively analyzed.The patients were divided into control group and observation group according to the random number table method,with 50 patients in each group.The control group was treated with moisture exposed burn ointment,and the observation group was treated with silver sulfadiazine combined with moisture exposed burn ointment.The wound healing(wound healing time,granulation growth time,scar incidence),wound secretion,pain degree and adverse reactions were compared between the two groups.Results:The wound healing time and granulation growth time of the observation group were shorter than those of the control group,and the incidence of scar was lower than that of the control group,the differences were statistically significant(P<0.05).The overall wound secretion of the observation group was less than that of the control group,and the overall pain degree was lighter than that of the control group(P<0.05)).There was no significant difference in the incidence of adverse reactions between the two groups during treatment(P>0.05).Conclusion:Silver sulfadiazine combined with moisture exposed burn ointment can accelerate wound healing for second degree burns,granulation growth,reduce wound secretions and relieve pain,and the combined treatment does not increase adverse reactions and has good safety.

BurnsSulfamethoxazole silverMoisture exposed burn ointmentHealPain

林斌、郭洪耀

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南阳市中医院烧伤创面修复科,河南 南阳 473000

烧伤 磺胺嘧啶银 湿润烧伤膏 愈合 疼痛

河南省卫生健康委中医临床研究科研项目

2019JDZX2114

2024

中国药物滥用防治杂志
中国药物滥用防治协会 军事医学科学院毒物药物研究所

中国药物滥用防治杂志

影响因子:0.584
ISSN:1006-902X
年,卷(期):2024.30(8)