首页|自拟乳宁煎剂联合他莫昔芬治疗乳腺增生症的效果

自拟乳宁煎剂联合他莫昔芬治疗乳腺增生症的效果

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目的:探讨自拟乳宁煎剂联合他莫昔芬治疗乳腺增生症(HMG)的临床效果.方法:依据随机数字表法将荥阳市人民医院 2022 年 1 月—2023 年 12 月收治的 118 例HMG患者分为对照组(n=59,他莫昔芬)和观察组(n=59,自拟乳宁煎剂+他莫昔芬),两组均持续治疗 2 个月.比较两组临床疗效、中医证候评分、性激素水平及不良反应.结果:观察组临床总有效率高于对照组(P<0.05);治疗 2 个月,两组中医证候评分、雌二醇、催乳素水平均较治疗前降低,且观察组低于对照组(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05).结论:自拟乳宁煎剂联合他莫昔芬可提高HMG的治疗效果,改善临床症状、性激素水平,且未明显增加不良反应的发生.
Effect of Self-made Runing Decoction Combined with Tamoxifen in the Treatment of Hyperplasia of Mammary Glands
Objective:To investigate the clinical efficacy of a self-made Runing decoction combined with tamoxifen in the treatment of hyperplasia of mammary glands(HMG).Methods:According to the random number table method,118 patients with HMG admitted to Xingyang People's Hospital from January 2022 to December 2023 were divided into control group(n=59,tamoxifen)and observation group(n=59,self-made Runing decoction+tamoxifen).Both groups were treated continuously for 2 months.The clinical efficacy,TCM syndrome score,sex hormone level and adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).After 2 months of treatment,the scores of TCM syndromes,estradiol and prolactin levels in the two groups were lower than those before treatment,and those in the observation group were lower than the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Self-made Runing decoction combined with tamoxifen can improve the therapeutic effect of HMG,improve clinical symptoms and sex hormone levels,and do not significantly increase the incidence of adverse reactions.

Hyperplasia of mammary glandsTamoxifenSelf-made Runing Decoction

李岚岚、吴盟

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荥阳市人民医院 乳腺科门诊,河南 荥阳 450100

荥阳市人民医院 门诊部,河南 荥阳 450100

乳腺增生 他莫昔芬 自拟乳宁煎剂

河南省医学教育研究项目

Wjlz2020097

2024

中国药物滥用防治杂志
中国药物滥用防治协会 军事医学科学院毒物药物研究所

中国药物滥用防治杂志

影响因子:0.584
ISSN:1006-902X
年,卷(期):2024.30(8)