Effect of Reduning Injection Combined with Budesonide Suspension in the Treatment of Bronchial Pneumonia
Objective:To study the effect of Reduning injection combined with budesonide suspension on bronchial pneumonia.Methods:A total of 120 children with bronchial pneumonia admitted to our hospital from January 2022 to January 2024 were randomly divided into control group and observation group,with 60 children in each group.The control group was treated with budesonide suspension,and the observation group was combined with Reduning injection.The lung function indexes(FEV1/FVC,MMF,VCmax,PEF,MVV and FEV1%expected value),symptom scores,inflammatory factor indexes[serum procalcitonin(PCT),tumor necrosis factor-α(TNF-α),interleukin-4(IL-4),insulin-like growth factor-Ⅱ(IGF-Ⅱ)]were compared between the two groups.Results:After treatment,the expected values of FEV1/FVC,MMF,VCmax,PEF,MVV and FEV1%in the observation group were higher than those in the control group(P<0.05).The symptom scores of the observation group were lower than those of the control group(P<0.05).The levels of serum PCT,TNF-α,IGF-Ⅱ and IL-4 in the observation group were lower than those in the control group(P<0.05).Conclusion:Reduning injection combined with budesonide suspension has a significant effect on bronchial pneumonia,which can significantly reduce symptoms and improve lung function.The mechanism may be related to the down-regulation of serum PCT,TNF-α,IGF-II and IL-4 levels.
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