Anesthetic Effect Analysis of Different Concentrations of Ropivacaine Combined with Dexmedetomidine Erector Spinae Plane Block in Thoracoscopic Pulmonary Wedge Resection
Objective:To compare the effects of different concentrations of ropivacaine combined with dexmedetomidine erector spinae plane (ESP) block in thoracoscopic pulmonary wedge resection. Methods:A total of 120 patients with lung cancer who underwent thoracoscopic pulmonary wedge resection from July 2020 to July 2023 were selected. All patients were treated with ropivacaine combined with dexmedetomidine ESP block. According to the concentration of ropivacaine,they were divided into 3 groups,with 40 patients in each group. The concentration of ropivacaine in group A was 0.25％,group B was 0.375％,and group C was 0.50％. The anesthesia block,pain degree,hemodynamics,sufentanil dosage and adverse reactions were compared among the three groups. Results:The onset time of block in group C was shorter than that in group B and group A,and that in group B was shorter than that in group A (P<0.05). At 12 h,24 h and 48 h after operation,there was no significant difference in Visual Analogue Scale (VAS) scores among the three groups (P>0.05). At 8 h after operation,the VAS scores of group C and group B were lower than those of group A,and the VAS score of group C was lower than that of group B (P<0.05). There was no significant difference in mean pulse pressure (MAP) and heart rate (HR) between the three groups at T0,T1,T2 and T3 (P>0.05). The dosage of sufentanil in group B and group C was less than that in group A (P<0.05). There was no significant difference in the incidence of adverse reactions within 48 h after operation among the three groups (P>0.05). Conclusion:The analgesic effects of 0.375％ and 0.50％ ropivacaine combined with dexmedetomidine ESP block in thoracoscopic pulmonary wedge resection are similar,but based on the risk of toxic reaction of local anesthetics,0.375％ ropivacaine combined with dexmedetomidine ESP block is preferred.
万方数据
维普
