Comparison of the Effects of Different Concentrations of 5-aminolevulinic Acid Photodynamic Therapy in the Adjuvant Treatment of Facial Intractable Flat Warts
Objective:To explore the effect of 10％ photodynamic therapy of 5-amino-ketovalerate in the treatment of patients with intractable facial plana warts and its influence on peripheral blood T lymphocyte subsets and immunoglobulin IgG. Methods:A total of 95 patients with intractable facial plana plana admitted to the Dermatology and Venereology Department of Hebi Hospital of Traditional Chinese Medicine from March 2019 to March 2022 were selected as the study objects,and were divided into control group (47 patients) and observation group (48 patients). Both groups were treated with retinoic acid cream combined with recombinant human interferon alpha-2B gel. On this basis,the control group was treated with 5％ of 5-aminoketovaleric acid photodynamic therapy,and the observation group was treated with 10％ of 5-aminoketovaleric acid photodynamic therapy. The clinical efficacy,immune function,recurrence rate and adverse reactions within 1 year of follow-up were compared between the two groups. Results:There were no significant differences in the incidence of adverse reactions,CD4+,CD8+,CD4+/CD8+and IgG levels between the two groups (P>0.05). The recurrence rate of the observation group was lower than that of the control group at 1 year follow-up,and the total effective rate was higher than that of the control group (P<0.05). Conclusion:Compared with 5％ of 5-amino-ketovaleric acid photodynamic therapy,10％ of 5-amino-ketovaleric acid photodynamic therapy has the same effect in improving the immune function of patients with intractable facial plana verruca,but it has better clinical efficacy and higher safety.
Different concentration5-amino-ketovalerate photodynamic therapyIntractable flat warts of the faceT lymphocyte subsets
万方数据
维普
