Effect of Mometasone Furoate Nasal Spray Combined with Cromoganaphenamine Nasal Spray in the Treatment of Children with Adenoidal Hypertrophy After Operation
Objective:To observe the clinical effect of mometasone furoate nasal spray combined with cromaridine methylamine nasal spray in children after adenoidectomy. Methods:A total of 160 children who underwent adenoid plasma radiofrequency ablation in the Quanzhou Children's Hospital from July 2022 to July 2023 were randomly divided into control group and observation group,with 80 children in each group. The control group was treated with normal saline nasal spray and mometasone furoate nasal spray,while the observation group was treated with carminamine nasal spray+mometasone furoate nasal spray. The scores of body inflammation,total nasal symptom score (TNSS) and Pittsburgh sleep quality index (PSQI) at multiple time points after operation were compared between the two groups,and the incidence of adverse reactions was counted. Results:The levels of IFN-γ and IL-4 in the observation group were lower than those in the control group on the 21st day after operation,and the TNSS score and PSQI score on the 3rd and 5th day after operation were lower than those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion:The early application of mometasone furoate nasal spray combined with cromoganaphenamine nasal spray in children with adenoidal hypertrophy after operation can significantly benefit. It can improve the postoperative nasal symptoms,inhibit the degree of inflammatory response,improve the quality of sleep,and does not increase the risk of adverse reactions.
万方数据
维普
