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ICP-MS法比较毛山药和光山药重金属及有害元素含量

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目的:比较毛山药和光山药中铜、汞、铅、砷、镉5种重金属及有害元素的含量.方法:采用微波消解法制备供试品溶液,以锗、铟、铋为内标,电感耦合等离子体质谱(ICP-MS)测定毛山药和光山药中铜、汞、铅、砷、镉5种元素的含量.结果:铜、汞、铅、砷、镉5种待测元素的线性关系良好(r≥0.999 5),回收率为82.4%~103.6%;RSD的范围为2.4%~5.9%.含量测定结果显示,和毛山药相比,光山药中5种重金属及有害元素含量均明显下降,铜残留量下降60.41%~73.57%.结论:和毛山药相比,光山药中含有更低含量的重金属及有害元素残留量.
Comparison the Content s of Heavy Metals and Harmful Elements in Dioscoreae Rhizoma by ICP-MS
Objective:To compare the contents of five heavy metals and harmful elements(Cu,Pb,As,Cd and Hg)in Maoshanyao and Guangshanyao.Methods:The sample solution was prepared by microwave digestion,and the contents of Cu,Pb,As,Cd and Hg were determined by inductively coupled plasma mass spectrometry(ICP-MS)with Germanium,indium and bismuth as internal standard.Results:The linear relationships of Cu,Pb,As,Cd and Hg were good(r≥0.999 5),and the recoveries were 82.4%-103.6%.RSD range was 2.4%to 5.9%.The content determination results showed that compared with Maoshanyao,the content of five heavy metals and harmful elements in Guangshanyao significantly decreased,and the proportion of copper residue reduction was 60.41%-73.57%.Conclusion:Compared with Maoshanyao,Guangshanyao contains lower levels of heavy metals and harmful elements residues.

Dioscoreae RhizomaMaoshanyaoGuangshanyaoHeavy metals and harmful elementsInductively coupled plasma mass spectrometry(ICP-MS)

杨铭、赵磊、昝珂

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济宁市食品药品检验检测研究院,山东济宁 272100

四平市食品药品检验所,吉林四平 136000

长春中医药大学药学院,吉林长春 130117

中国食品药品检定研究院,北京 102629

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山药 毛山药 光山药 重金属及有害元素 电感耦合等离子体质谱

2024

中国药物评价
国家食品药品监督管理局信息中心

中国药物评价

影响因子:1.09
ISSN:2095-3593
年,卷(期):2024.41(4)