A Systematic Review and Meta-analysis of Jinkui Shenqi Pill in the Treatment of Type 2 Diabetes Mellitus
Objective:To evaluate the clinical efficacy and safety of Jinkui Shenqi pills in the treatment of type 2 diabetes mellitus.Methods:CNKI,VIP,Chinese Biomedical Literature,Wanfang,Pubmed,Embase Database and Cochrane Database were searched and the randomized controlled trials on Jinjishenqi pills in the treatment of type 2 diabetes from base-building to Jul.27th,2023 were screened out.The patients in the control group were treated by conventional Western medicine treatment and the patients in the experimental group were treated by Jinkui Shenqi pill on the basis of usual treatment.Literature screening and data extraction were conducted by specific researchers.The Cochrane risk assessment tool was adopted to assess the quality of the included literature.Indicators were analyzed by using RevMan5.3.Results:Finally 9 RCTs were included,with a total of 895 patients.Meta-analysis showed that the clinical total effective rate[OR=4.39,95％CI=(2.84,6.80),P＜0.000 01],postprandial 2 hours blood glucose(PBG)[MD=2.12,95％CI=(2.74,1.50),P＜0.000 01],Fasting blood glucose(FBG)[MD=0.66,95％CI=[0.86,0.47],P＜0.000 01)and glycosylated hemoglobin(HbAlc)[MD=0.79,95％CI=(1.26,0.32),P=0.001]were statistically different.Conclusion:The existing figures show that Jinkui Shenqi pill can significantly improve the clinical effective rate of type 2 diabetes and reduce the content of PBG,FBG and HbAlc.
万方数据
维普
