中国药物与临床2024,Vol.24Issue(2) :69-74.DOI:10.11655/zgywylc2024.02.001

妊娠期高血压疾病中Ca2+通道作用机制及治疗策略

Mechanisms and therapeutic approaches targeting calcium channels in hypertensive disorder complicating pregnancy

樊博扬 武星辰 胡丽燕
中国药物与临床2024,Vol.24Issue(2) :69-74.DOI:10.11655/zgywylc2024.02.001

妊娠期高血压疾病中Ca2+通道作用机制及治疗策略

Mechanisms and therapeutic approaches targeting calcium channels in hypertensive disorder complicating pregnancy

樊博扬 1武星辰 1胡丽燕2
扫码查看

作者信息

  • 1. 山西医科大学附属山西省儿童医院妇产科,山西太原 030013
  • 2. 山西省儿童医院山西省妇幼保健院妇产科,山西太原 030013
  • 折叠

摘要

妊娠期高血压疾病对母体和胎儿的健康都会产生不良影响,妊娠期高血压疾病患者的血管平滑肌细胞中Ca2+通道的表达水平较正常妊娠期患者高,这可能使得细胞内Ca2+浓度增加,引发血管收缩和血压升高.本文拟论述妊娠期高血压疾病中Ca2+通道的作用机制,并探讨Ca2+通道在该疾病治疗策略中的价值,为妊娠期高血压疾病的临床诊断和治疗提供思路和方法.

Abstract

Gestational hypertension can have adverse effects on both the mother's and fetus's health.The expression level of calcium ion channels in vascular smooth muscle cells is elevated in patients with gestational hypertension compared to normal pregnancy,which may lead to increased intracellular calcium ion concentration,resulting in vasoconstriction and elevated blood pressure.The purpose of this article is to discuss the mechanism of action of calcium ion channels in gestational hypertension and investigate their potential value in the treatment strategy for this disease,providing novel ideas and methods for the clinical diagnosis and treatment.

关键词

高血压,妊娠性/钙通道/调控机制/临床方案

Key words

Hypertension pregnancy-induced/Calcium channels/Regulation mechanism/Clinical pro-tocols

引用本文复制引用

出版年

2024
中国药物与临床
中国医院协会

中国药物与临床

影响因子:0.846
ISSN:1671-2560
参考文献量30
段落导航相关论文