Effect and safety analysis of traditional Chinese medicine combined with Femoston on hemorheology indi-cators in patients with intrauterine adhesion
Objective To explore the clinical efficacy of traditional Chinese medicine combined with Fenmoton in intrauterine adhesions,as well as the impact on hemorheological indicators and safety in patients.Methods A total of 92 patients with intrauterine adhesions who visited Puyang Maternal and Child Health Hos-pital from March 2020 to April 2022 were divided into a control group and an experimental group according to treatment method,with 46 cases in each group.The control group was treated with Femoston,while the experi-mental group was treated with Femoston combined with traditional Chinese medicine.Both groups were treated for 3 menstrual cycles.The therapeutic effects,intrauterine adhesion scores(adhesion type,menstrual status,adhesion range)before and after treatment,resistance index(RI)and pulsatility index(PI)of uterine artery,endometrial thickness,plasma viscosity,whole blood low-shear viscosity,whole blood high-shear viscosity levels,as well as the occurrences of rash,gastrointestinal reactions,headache,and breast tenderness before and after treatment were compared between two groups.Results The total effective rate of the experimental group(98％)was higher than that of the control group(80％).After treatment,the intrauterine adhesion scores(adhesion type,menstrual status,adhesion range),RI,PI,plasma viscosity,whole blood low-shear viscosity,and whole blood high-shear viscosity levels in the experimental group were(2.13±0.31)points,(2.01±0.61)points,(2.19±0.45)points,0.69±0.11,1.79± 0.31,(1.30±0.08)mPa·s,(7.01±0.09)mPa·s,and(3.12±0.12)mPa·s respectively.The above indicators in the con-trol group were(2.52±0.53)points,(2.43±0.59)points,(2.54±0.32)points,0.85±0.10,2.02±0.52,(1.41±0.09)mPa·s,(7.62±0.12)mPa·s,and(3.65±0.21)mPa·s,respectively.These indicators in the experimental group were lower than those in the control group and before treatment.And the endometrial thickness in the experimental group(3.56±0.36)mm was thinner than that in the control group(4.02±0.23)mm and before treatment(P＜0.05).The dif-ference in adverse reactions between the two groups(13％vs 4％)was not statistically significant(P＞0.05).Conclusion The combination of Femoston and traditional Chinese medicine can improve the clinical efficacy of patients with intrauterine adhesions,reduce the risk of intrauterine adhesions and resistance in the uterine artery,increase endometrial thickness,promote endometrial repair,restore endometrial blood flow,and promote patient recovery.This treatment method has good safety and can provide reference for the clinical treatment of intrauterine adhesions.
DecoctionsFemostonIntrauterine adhesionBlood viscosityWhole blood has low tan-gential viscosityWhole blood has high tangential viscosity
万方数据
维普
