Distribution characteristics and drug resistance of pathogenic bacteria cultured in sputum of 140 children with infectious pneumonia
Objective To analyze the distribution and drug resistance of pathogenic bacteria in sputum culture of 140 children with infectious pneumonia.Methods We collected sputum bacterial culture specimens form 140 children with pneumonia who were treated at Nanyang Central Hospital from June 2022 to June 2023,and then conducted bacterial and drug sensitivity experiments.An analysis was conducted to determine the distri-bution and composition of pathogenic bacteria in 140 children with infectious pneumonia.Furthermore,the resis-tance of antibiotics such as Haemophilus influenzae,Moraxella catarrata,and Streptococcus pneumoniae were an-alyzed.Results The sputum bacterial culture of 140 children showed that 60 cases(42.9％)were positive.A total of 68 strains of pathogenic bacteria were isolated,among which the number of gram-negative bacteria,gram-positive bacteria and fungi were 40,26 and 2,accounting for 58.8％,38.2％and 2.9％,respectively.Among all pathogenic strains,there were 22,20,11 and 4 strains of Haemophilus influenzae,Streptococcus pneumoniae,Moraxella catarrhalis and Staphylococcus aureus,with the detection rates of 15.7％,14.3％,7.9％and 2.9％,respectively.For children with infectious pneumonia caused by streptococcus pneumoniae nave a low rate of resistance to penicillin and levofloxacin(11.1％,5.6％).Children with infective pneumonia caused by Haemophilus influenzae and Moraxella catarrhal have alow rate of resistance to cefotaxime and amoxicillin(7.1％,22.7％,0).Conclusion The main pathogenic bacteria of 140 children with infectious pneumonia were Haemophilus influenzae,Moraxella catarrhal,Streptococcus pneumoniae,etc.For children with infectious pneumonia caused by streptococcus pneumoniae,penicillin and levofloxacin can be used for treatment,while for children with infectious pneumonia caused by Haemophilus influenzae and Moraxella catarrhal,cefotaxime and amoxicillin can be used for treatment.
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维普
