Related factors leading to dental caries in children
Objective To analyze the relationship between oral Helicobacter pylori(HP)infection,salivary trace elements and dental caries in children.Methods A total of 124 children with dental caries who visited the Lishui People's Hospital from February 2021 to March 2023 were selected as the study group,while another 124 children without dental caries who visited the hospital for other reasons during the same period were selected as the control group.Both groups of children were tested for oral Helicobacter pylori,saliva pH,and concentrations of sodium,calcium,potassium,chloride,fluoride,and phosphorus ions.Correlation analysis was used to investigate the association between the severity of dental caries,oral HP infection as well as salivary trace elements.Results The HP-DNA copy number and HP positive ratio in type Ⅳ dental caries were significantly higher than in type Ⅲ,type Ⅱ,type Ⅰ,and type 0,with statistically significant differences(P＜0.05).The NO level in the study group was higher than that in the control group,and the pH value was lower than that in the control group,with a statistically significant difference(P＜0.05).The NO level in type Ⅳ dental caries was higher than in type Ⅲ,type Ⅱ,and type Ⅰ,while the pH value in type Ⅳ was lower than in type Ⅲ,type Ⅱ,and type Ⅰ.The differences were statistically significant(P＜0.05).The copy number of HP-DNA was positively correlated with NO level and negatively correlated with pH value(r=-0.564,P＜0.05).The condition of dental caries was positively correlated with HP-DNA copy number and NO level(r=0.651,P＜0.05),and negatively correlated with pH value(r=-0.671,P＜0.05).Conclusion Children with dental caries have varying degrees of HP infection as well as changes in salivary trace elements and pH levels.The degree of infection is correlated with the severity of dental caries.
MouthHelicobacter pyloriSalivaDental cariesCorrelation of data
万方数据
维普
