Analgesic and sedative effects of dexmedetomidine nasal drops on laparoscopic hernioplasty in children and the quality of extubation
Objective To investigate the analgesic and sedative effects of dexmedetomidine nasal drops on laparoscopic hernioplasty in children and the quality of extubation.Methods A total of 94 children who un-derwent laparoscopic hernioplasty in Jinhua Maternal and Child Health Hospital from March 2021 to September 2022 were selected,and they were divided into a control group and an observation group according to different anesthetic drugs,with 47 cases in each group.The observation group received 1 μg/kg dexmedetomidine nasal drops,while the control group received 0.9％sodium chloride injection nasal drops at equal volume.Compared mean arterial pressure(MAP),heart rate(HR),and blood oxygen saturation(SpO2)levels at the following time points:before anesthesia induction(T0),immediately after intubation(T1),5 minutes after intubation(T2),at the end of surgery(T3),and immediately after intubation(T4).Additionally,the visual analog scales(VAS),Ramsay sedation score(RSS),and restlessness rate at 10,20,30,and 40 minutes after extubation were compared.Results At T1,T2,T3 and T4,the levels of MAP and HR in the observation group were lower than those in the control group(P＜0.05).There were no statistically significant differences in the levels of SpO2 between the two groups at T1,T2,T3,and T4(P＞0.05).The VAS and SAV in the observation group were lower than those in the control group at 20,30 and 40 minutes after extubation(P＜0.05).The extubation time,awakening time,PACU retention time and restlessness rate in the observation group were lower than those in the control group(P＜0.05).Conclu-sion Dextrmetomidine nasal drops can effectively stabilize the hemodynamics of children,effectively improve seda-tion and analgesia,and enhance the quality of extubation.
万方数据
维普
