Effect of oxycodone combined with sevoflurane in gynecological laparoscopic surgery
Objective To assess the effect of oxycodone combined with sevoflurane during gynecological laparoscopic surgery.Methods Between January 2019 to December 2022,a total of 90 patients who underwent gynecological laparoscopic surgery under general anesthesia were selected as study subjects in First People's Hospital of Taizhou.These patients were assigned to an observation group and a control group according to treat-ment,with 45 patients in each group.Both groups received sevoflurane inhalation anesthesia.Additionally,the ob-servation group was administered oxycodone at the end of surgery,while the control group received dexmedetomi-dine.Postopera-tive outcomes were evaluated using the Visual Analogue Scale(VAS)for pain,Ramsay Sedation Score for sedation levels post-extubation,and the Richmond Agitation Sedation Scale(RASS)at various time points.These metrics were compared between the two groups to assess any differences in postoperative complica-tions.Results The VAS scores of the observation group were significantly lower than those of the control group at 1 h,6 h,12 h,and 24 h postoperatively(P＜0.05).Furthermore,the Ramsay Sedation Scores in the observation group were higher compared to the control group at 5 min,10 min,20 min,and 60 min post-extubation(P＜0.05).Additionally,the RASS scores of the observation group were lower than those of the control group at 5 min and 10 min after catheter removal(P＜0.05).However,there was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The combination of oxycodone with sevoflurane effectively enhances analgesia and sedation scores among gynecological patients following laparoscopic surgery,while also reducing RASS scores.
Emergence deliriumHydroxycodoneHeptafluraneLaparoscopic surgery
万方数据
维普
